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Filtered Search Results
Sigma Aldrich Ethyl 5-methyl-3-p-tolylisoxazole-4-carboxylate
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
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Sigma Aldrich N,N'-Dimethylurea
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
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| CAS | 96-31-1 |
|---|
Sigma Aldrich 1-(4-METHOXYPHENYL)-3-P-TOLYL-1H-PYRAZOL-4-OL
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
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Aobchem AOBCHEM
5000864042 N-CYCLOPENTYLBENZAMIDE 250MG
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Medchemexpress LLC Methyl 2,5-dihydroxycinnamate | 63177-57-1 | MFCD00132932 | 99.8% | 194.18 | C10H10O4 | 10 MG
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Methyl 2,5-dihydroxycinnamate is a small-molecule research chemical described as an erbstatin analog that potently inhibits epidermal growth factor receptor (EGFR) kinase activity. It is supplied as a solid and as DMSO solutions for laboratory research and biochemical assays. Intended for research use only; not for human or clinical applications.
- Potent inhibitor of EGFR kinase activity.
- Erbstatin analog small-molecule structure.
- Available as solid and as 10 mM solution in DMSO.
- High purity suitable for analytical and biological assays.
- Documented identifiers and physicochemical data for compound tracking.
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Medchemexpress LLC 3- 2-ChloropyriMidin 5g | 5G
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3- 2-ChloropyriMidin 5g | 5G
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Apexbio Technology LLC Sulfaphenazole 526-08-9 250mg
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Sulfaphenazole (CAS 526-08-9) is a small-molecule inhibitor targeting cytochrome P450 2C9 (CYP2C9) It is designed to selectively inhibit CYP2C9-mediated drug metabolism thereby informing metabolic pathway studies and investigation of drug-drug interactions Sulfaphenazole exerts its biological activity primarily through competitive inhibition of CYP2C9 In in vitro assays sulfaphenazole demonstrates potent inhibition with a reported Ki value of approximately 0 3 M for human CYP2C9 Based on these pharmacological properties sulfaphenazole holds research potential in evaluating CYP2C9-mediated metabolic processes and associated drug interactions
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Medchemexpress LLC Ethyl 3-oxopentanoate | 4949-44-4 | 97.9% | C7H12O3 | 5 G
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Ethyl 3-oxopentanoate is an organic ester compound commonly used as a reactant or solvent in organic synthesis. It serves as an important raw material for the preparation of pharmaceuticals, food flavors, spices, and other products. It is also widely used in some industrial productions due to its stability and reactivity in certain chemical reactions. It is for research use only.
- Used as a reactant or solvent in organic synthesis
- Important raw material for pharmaceuticals
- Important raw material for food flavors and spices
- Widely used in industrial productions
- Plays a role in chemical research and industry
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Apexbio Technology LLC Dasatinib Monohydrate 863127-77-9 100mg
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Dasatinib Monohydrate (CAS 863127-77-9) is a small molecule inhibitor primarily targeting Bcr-Abl and Src family tyrosine kinases with IC50 values of 3 0 nM and 0 55 nM respectively It acts as an ATP-competitive inhibitor and demonstrates broad-spectrum antiproliferative activity in both hematological and solid tumor cell models Dasatinib is effective in suppressing wild-type and the majority of imatinib-resistant BCR-ABL kinase variants In murine studies oral administration of dasatinib reduced disease progression and bioluminescence levels in BCR-ABL-driven leukemia models Dasatinib is widely employed in research on kinase signaling and drug resistance mechanisms in Ph-positive leukemias
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431272 HELICID 250MG
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eMolecules 2467965-71-3 | EED226-COOH | AstaTech335.323 | C17H13N5O3 | 95.000 | OC(=O)c1ccc(cc1)-c1cnc(NCc2ccco2)n2cnnc12 | 0.1g | 562552109
EED226-COOH | AstaTech | 2467965-71-3335.323 | C17H13N5O3 | 95.000 | OC(=O)c1ccc(cc1)-c1cnc(NCc2ccco2)n2cnnc12 | 0.1g | 562552109
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![Medchemexpress LLC Thiazolium,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-(4,6,6-trihydroxy-4,6-dioxido-3,5-dioxa-4,6-diphosphahex-1-yl)-,chloride (1:1) | 154-87-0 | 99.9% | 460.77 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000435599-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC Thiazolium,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-(4,6,6-trihydroxy-4,6-dioxido-3,5-dioxa-4,6-diphosphahex-1-yl)-,chloride (1:1) | 154-87-0 | 99.9% | 460.77 | 1 ML
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Thiamine pyrophosphate is the coenzyme form of Vitamin B1, acting as a required intermediate in several crucial metabolic complexes. It is essential for oxidative phosphorylation and the pentose phosphate pathway, functioning as a cofactor for α-ketoacid dehydrogenases.
- Acts as a cofactor for α-ketoacid dehydrogenases
- Inhibits ischemia-reperfusion induced oxidative damage
- Prevents Cisplatin induced cardiotoxicity
- Reduces associated oxidative stress and heart injury
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Medchemexpress LLC N2,N2-Dimethylguanosine | 2140-67-2 | 99.4% | 311.29 | 50 MG
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N2,N2-Dimethylguanosine is a methylated nucleoside present in RNA and a structural modification component of tRNA. It hinders reverse transcriptase-mediated cDNA synthesis and is a key modification affecting sequencing efficiency in high-throughput RNA sequencing. It can be selectively demethylated into N2-methylguanosine by AlkB mutant enzymes (such as D135S/L118V), reducing hindrance to reverse transcription.
- Methylated nucleoside present in RNA and a structural modification component of tRNA.
- Hinders reverse transcriptase-mediated cDNA synthesis.
- Key modification affecting sequencing efficiency in high-throughput RNA sequencing.
- Can be converted to N2-methylguanosine by AlkB mutant enzymes to reduce hindrance to reverse transcription.
- Appears as a white to off-white solid.
- Initial source: Endogenous metabolite.
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Ambeed AMBEED
5000866706 METHYL 6-BROMOPYRAZOLO15-A 1GR
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5000702645 GRAVEOLINE 250MG
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